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 | Muscle and Bones |
Knee and hip joint replacement surgery is increasingly applied, both in the young and elderly population, due to sport activities and the fragility of bones, respectively. NIRM aims to:
- Identify and characterize mesenchymal stem cells and pericytes and their genetic and epigenetic programs for implementation in treatment strategies for bone, cartilage, vascular, smooth and skeletal muscle repair and regeneration.
- Develop and implement nanotechnology and high throughput screening in biological and material-driven research on skeletal regeneration.
- Develop bio-inspired scaffolds with an orchestrated activation/inhibition of local cellular processes, in particular stem cell recruitment and differentiation.
- Gain fundamental biological insight into the complex biology of bone and cartilaginous tissues in the context of regenerative medicine.
